LOC327709 glutathione S-transferase M1 [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: LOC327709
Gene description: glutathione S-transferase M1
See related: BGD:BT18262; Ensembl:ENSBTAG00000058591
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: GSTM1
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Genomic context

Location:: chromosome: 3

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	3	NC_037330.1 (33690883..33701648, complement)

Chromosome 3 - NC_037330.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

missense mutation (rs135955605) associated with significant decrease of sperm motility and ATP content
Title: Missense mutation in glutathione-S-transferase M1 gene is associated with sperm motility and ATP content in frozen-thawed semen of Holstein-Friesian bulls.

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General gene information

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Markers

MARC_4145-4146:996679427:1 (e-PCR)
- UniSTS:269333

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables glutathione transferase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in glutathione metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: glutathione S-transferase Mu 1

Names: GST class-mu 1; GSTM1-1

NP_787019.1

EC 2.5.1.18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175825.4 → NP_787019.1 glutathione S-transferase Mu 1

See identical proteins and their annotated locations for NP_787019.1

Status: PROVISIONAL

Source sequence(s)

BC102050

UniProtKB/Swiss-Prot

Q9N0V4

UniProtKB/TrEMBL

A5PKM0

Related

ENSBTAP00000023627.7, ENSBTAT00000023627.7

Conserved Domains (2) summary

cd03209
Location:92 → 211

GST_C_Mu; C-terminal, alpha helical domain of Class Mu Glutathione S-transferases

cd03075
Location:3 → 84

GST_N_Mu; GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...