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CG7322 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32880, updated on 9-Dec-2024

Summary

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Official Symbol
CG7322provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030968
Locus tag
Dmel_CG7322
See related
AllianceGenome:FB:FBgn0030968
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7322
Summary
Predicted to enable L-xylulose reductase (NADPH) activity and carbonyl reductase (NADPH) activity. Predicted to be involved in glucose metabolic process and xylulose metabolic process. Is expressed in adult head; adult heart; embryonic/larval fat body; and organism. Human ortholog(s) of this gene implicated in pentosuria. Orthologous to human DCXR (dicarbonyl and L-xylulose reductase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG7322 in Genome Data Viewer
Location:
17E1-17E1; 1-61 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18855873..18857757, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (18749906..18751790, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene PDGF- and VEGF-related factor 1 Neighboring gene hat-trick Neighboring gene shopper Neighboring gene Ubiquitin specific protease 39 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia. Otto N, et al. Nat Commun, 2018 Aug 29. PMID 30158546, Free PMC Article
  2. Studies on the glutathione S-transferase proteome of adult Drosophila melanogaster: responsiveness to chemical challenge. Alias Z, et al. Proteomics, 2007 Oct. PMID 17907271
  3. Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. Yoon WH, et al. Neuron, 2017 Jan 4. PMID 28017472, Free PMC Article
  4. Drosophila glia: Few cell types and many conserved functions. Yildirim K, et al. Glia, 2019 Jan. PMID 30443934
  5. A cross-species approach for the identification of Drosophila male sterility genes. Ibaraki K, et al. G3 (Bethesda), 2021 Aug 7. PMID 34849808, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables L-xylulose reductase (NADPH) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-xylulose reductase (NADPH) activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables carbonyl reductase (NADPH) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-glucuronate catabolic process to D-xylulose 5-phosphate ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in glucose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in xylulose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7322-PA
CG7322-PB
CG7322-PC
NP_001259693.1
NP_001285416.1
NP_573333.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    18855873..18857757 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_133105.3 → NP_573333.2  uncharacterized protein Dmel_CG7322, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573333.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYA6, Q9VWP2
    Related
    FBpp0074425
    Conserved Domains (1) summary
    cd05351
    Location:1 → 242
    XR_like_SDR_c; xylulose reductase-like, classical (c) SDRs

  2. NM_001298487.1 → NP_001285416.1  uncharacterized protein Dmel_CG7322, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285416.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYA6, Q9VWP2
    Conserved Domains (1) summary
    cd05351
    Location:1 → 242
    XR_like_SDR_c; xylulose reductase-like, classical (c) SDRs

  3. NM_001272764.1 → NP_001259693.1  uncharacterized protein Dmel_CG7322, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259693.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYA6, Q9VWP2
    Conserved Domains (1) summary
    cd05351
    Location:1 → 242
    XR_like_SDR_c; xylulose reductase-like, classical (c) SDRs
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SYA6 Q8SYA6
Q9VWP2 Q9VWP2

Gene LinkOut

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