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Inx5 Innexin 5 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32901, updated on 9-Dec-2024

Summary

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Official Symbol
Inx5provided by FlyBase
Official Full Name
Innexin 5provided by FlyBase
Primary source
FLYBASE:FBgn0030989
Locus tag
Dmel_CG7537
See related
AllianceGenome:FB:FBgn0030989
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7537; Dm-inx5; Dmel\CG7537; FBpp0074467; Innexin5; inx-5; inx5
Summary
Predicted to enable gap junction channel activity. Predicted to be involved in intercellular transport and phototransduction. Located in gap junction. Is expressed in spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Inx5 in Genome Data Viewer
Location:
18A4-18A4; 1-62 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19168777..19170883, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19062810..19064916, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein at 18B Neighboring gene Odorant-binding protein 18a Neighboring gene mir-4959 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Recent findings in evolution and function of insect innexins. Hasegawa DK, et al. FEBS Lett, 2014 Apr 17. PMID 24631533
  2. Anatomical distribution and functional roles of electrical synapses in Drosophila. Ammer G, et al. Curr Biol, 2022 May 9. PMID 35385694
  3. Gap junctions in Drosophila: developmental expression of the entire innexin gene family. Stebbings LA, et al. Mech Dev, 2002 May. PMID 11960713
  4. A possible flip-flop genetic mechanism for reciprocal gene expression. Chiusano ML, et al. FEBS Lett, 2005 Sep 12. PMID 16139277
  5. Evolutionary analyses of gap junction protein families. Abascal F, et al. Biochim Biophys Acta, 2013 Jan. PMID 22366062

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables gap junction channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in intercellular transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in phototransduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in gap junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in gap junction IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
innexin 5
Names
CG7537-PB
Innexin-5
Inx5-PB
inx5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    19168777..19170883 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_133125.3 → NP_573353.2  innexin 5 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573353.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8WHD8, Q8MZL3, Q9VWL5
    Related
    FBpp0074467
    Conserved Domains (1) summary
    pfam00876
    Location:21 → 405
    Innexin; Innexin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VWL5.2 Q9VWL5

Gene LinkOut

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