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Ulp1 Ulp1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32910, updated on 9-Dec-2024

Summary

Official Symbol
Ulp1provided by FlyBase
Official Full Name
Ulp1provided by FlyBase
Primary source
FLYBASE:FBgn0027603
Locus tag
Dmel_CG12359
See related
AllianceGenome:FB:FBgn0027603
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH02751; CG12359; Dmel\CG12359; DmUlp1; ulp1
Summary
Enables deSUMOylase activity. Involved in several processes, including negative regulation of signal transduction; neuron projection morphogenesis; and protein destabilization. Located in cytoplasm and nuclear inner membrane. Part of nuclear pore. Is expressed in several structures, including germarium; germline cell; gonad; and larval central nervous system. Orthologous to human SENP2 (SUMO specific peptidase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Ulp1 in Genome Data Viewer
Location:
18B1-18B1; 1-62 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19202103..19208187, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19096136..19102220, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Mucin related 18B

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cysteine-type peptidase activity  
enables deSUMOylase activity  
enables deSUMOylase activity PubMed 
enables deSUMOylase activity PubMed 
Component Evidence Code Pubs
located_in cytoplasm PubMed 
located_in nuclear inner membrane PubMed 
part_of nuclear pore PubMed 
is_active_in nucleus  
located_in nucleus PubMed 

General protein information

Preferred Names
Ulp1
Names
CG12359-PA
Ulp1-PA
ubiquitin-like protein-specific protease 1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    19202103..19208187 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_133134.3 → NP_573362.1  Ulp1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573362.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VWK5, Q9Y160
    Related
    FBpp0074462
    Conserved Domains (2) summary
    pfam09528
    Location:200 → 580
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    pfam02902
    Location:1331 → 1506
    Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain
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