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Rbm44 RNA binding motif protein 44 [ Mus musculus (house mouse) ]

Gene ID: 329207, updated on 27-Nov-2024

Summary

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Official Symbol
Rbm44provided by MGI
Official Full Name
RNA binding motif protein 44provided by MGI
Primary source
MGI:MGI:2685663
See related
Ensembl:ENSMUSG00000070732 AllianceGenome:MGI:2685663
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm817
Summary
Enables protein homodimerization activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in cytoplasm and intercellular bridge. Orthologous to human RBM44 (RNA binding motif protein 44). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 5.5), liver E14 (RPKM 0.5) and 2 other tissues See more
Orthologs
human all
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Genomic context

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See Rbm44 in Genome Data Viewer
Location:
1 D; 1 46.08 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (91072695..91098521)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (91144973..91170799)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RAB17, member RAS oncogene family Neighboring gene leucine rich repeat (in FLII) interacting protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E4334 Neighboring gene STARR-positive B cell enhancer ABC_E3290 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:92961823-92961976 Neighboring gene predicted gene, 35443 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:93080001-93080198 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:93089975-93090287 Neighboring gene proteasome (prosome, macropain) 28 subunit, alpha pseudogene Neighboring gene receptor (calcitonin) activity modifying protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E9471

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification and characterization of RBM44 as a novel intercellular bridge protein. Iwamori T, et al. PLoS One, 2011 Feb 25. PMID 21364893, Free PMC Article
  2. E2F6 initiates stable epigenetic silencing of germline genes during embryonic development. Dahlet T, et al. Nat Commun, 2021 Jun 11. PMID 34117224, Free PMC Article
  3. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in intercellular bridge IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
RNA-binding protein 44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033408.5 → NP_001028580.1  RNA-binding protein 44

    See identical proteins and their annotated locations for NP_001028580.1

    Status: VALIDATED

    Source sequence(s)
    AC162883
    Consensus CDS
    CCDS15157.1
    UniProtKB/Swiss-Prot
    Q3V089
    UniProtKB/TrEMBL
    B9EKJ9
    Related
    ENSMUSP00000092286.2, ENSMUST00000094698.2
    Conserved Domains (1) summary
    cd12248
    Location:793 → 865
    RRM_RBM44; RNA recognition motif in RNA-binding protein 44 (RBM44) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    91072695..91098521
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529704.1 → XP_006529767.1  RNA-binding protein 44 isoform X2

  2. XM_006529702.1 → XP_006529765.1  RNA-binding protein 44 isoform X1

    See identical proteins and their annotated locations for XP_006529765.1

    UniProtKB/Swiss-Prot
    Q3V089
    UniProtKB/TrEMBL
    B9EKJ9
    Conserved Domains (1) summary
    cd12248
    Location:793 → 865
    RRM_RBM44; RNA recognition motif in RNA-binding protein 44 (RBM44) and similar proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3V089.1 GenPept UniProtKB/Swiss-Prot:Q3V089

Gene LinkOut

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