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dome - domeless

Enables several functions, including SOCS family protein binding activity; STAT family protein binding activity; and protein heterodimerization activity. Involved in several processes, including border follicle cell migration; cell surface receptor signaling pathway; and digestive tract development. Located in apical plasma membrane. Is expressed in several structures, including Kenyon cell; adult brain; follicle cell; gut section; and mushroom body. Used to study viral infectious disease. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 73 and autosomal recessive nonsyndromic deafness 84A. Orthologous to human PTPRQ (protein tyrosine phosphatase receptor type Q). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa