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Ubqn - Ubiquilin

Enables proteasome binding activity. Involved in amyloid precursor protein metabolic process and ubiquitin-dependent protein catabolic process. Located in cytosol. Is expressed in several structures, including adult head; embryonic brain; embryonic/larval midgut; larval muscle system; and larval nervous system. Used to study amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 15; frontotemporal dementia; and neurodegenerative disease. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and amyotrophic lateral sclerosis type 15. Orthologous to human UBQLN1 (ubiquilin 1); UBQLN2 (ubiquilin 2); and UBQLN4 (ubiquilin 4). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Ubqn

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Species Gene Architecture aa