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CG14230 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32984, updated on 9-Dec-2024

Summary

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Official Symbol
CG14230provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031062
Locus tag
Dmel_CG14230
See related
AllianceGenome:FB:FBgn0031062
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-18DEe; cg14230; clone 9.42; Dmel\CG14230; Nol8
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be active in nuclear speck. Orthologous to human NOL8 (nucleolar protein 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG14230 in Genome Data Viewer
Location:
18E1-18E2; 1-64 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19704176..19706417)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19598209..19600450)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cell division cycle 42 Neighboring gene Threonyl-carbamoyl synthesis 4 Neighboring gene uncharacterized protein Neighboring gene meso18E Neighboring gene long non-coding RNA:CR44889 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation of mutations in the Drosophila homologues of the human Neurofibromatosis 2 and yeast CDC42 genes using a simple and efficient reverse-genetic method. Fehon RG, et al. Genetics, 1997 May. PMID 9136014, Free PMC Article
  2. Identification of New Regulators of the Oocyte-to-Embryo Transition in Drosophila. Avilés-Pagán EE, et al. G3 (Bethesda), 2020 Sep 2. PMID 32690584, Free PMC Article
  3. Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells. Zirin J, et al. Proc Natl Acad Sci U S A, 2019 Jul 16. PMID 31262815, Free PMC Article
  4. An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. Avet-Rochex A, et al. BMC Dev Biol, 2010 Jun 11. PMID 20540764, Free PMC Article
  5. A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience. Evans CJ, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561251, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG14230-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    19704176..19706417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134505.3 → NP_608349.1  uncharacterized protein Dmel_CG14230 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608349.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VWD4
    Related
    FBpp0074556
    Conserved Domains (2) summary
    COG0724
    Location:3 → 115
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd00590
    Location:7 → 77
    RRM_SF; RNA recognition motif (RRM) superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VWD4.2 Q9VWD4

Gene LinkOut

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