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Dop2R - Dopamine 2-like receptor

Enables dopamine neurotransmitter receptor activity, coupled via Gi/Go. Involved in G protein-coupled dopamine receptor signaling pathway and anesthesia-resistant memory. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult deutocerebrum; anterior-posterior subdivision of organism; embryonic/larval anterior Malpighian tubule; ganglia; and gut section. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; drug dependence (multiple); end stage renal disease; movement disease (multiple); and nicotine dependence. Orthologous to several human genes including DRD3 (dopamine receptor D3). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to Dop2R

NCBI Orthologs

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Species Gene Architecture aa