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Cda4 Chitin deacetylase-like 4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33144, updated on 4-Jan-2025

Summary

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Official Symbol
Cda4provided by FlyBase
Official Full Name
Chitin deacetylase-like 4provided by FlyBase
Primary source
FLYBASE:FBgn0052499
Locus tag
Dmel_CG32499
See related
AllianceGenome:FB:FBgn0052499
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE51076; CG12447; CG13238; CG32499; CG9557; CG9558; DmCDA4; Dmel\CG32499
Summary
Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Located in perivitelline space. Is expressed in several structures, including adult brain cell body rind; embryonic dorsal epidermis; embryonic head epidermis; embryonic/larval tracheal section; and gut section. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Cda4 in Genome Data Viewer
Location:
20C3-20D1; 1-66 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (22583634..22632710, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (21985470..22034546, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Clusterin associated protein 1 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44997 Neighboring gene long non-coding RNA:CR44109 Neighboring gene long non-coding RNA:CR45464

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Domain organization and phylogenetic analysis of proteins from the chitin deacetylase gene family of Tribolium castaneum and three other species of insects. Dixit R, et al. Insect Biochem Mol Biol, 2008 Apr. PMID 18342249
  2. Identification of cis-regulatory modules encoding temporal dynamics during development. Potier D, et al. BMC Genomics, 2014 Jun 27. PMID 24972496, Free PMC Article
  3. Acute manipulation and real-time visualization of membrane trafficking and exocytosis in Drosophila. Glashauser J, et al. Dev Cell, 2023 Apr 24. PMID 37023749
  4. Tramtrack is genetically upstream of genes controlling tracheal tube size in Drosophila. Rotstein B, et al. PLoS One, 2011. PMID 22216153, Free PMC Article
  5. Identification of FGF-dependent genes in the Drosophila tracheal system. Stahl M, et al. Gene Expr Patterns, 2007 Jan. PMID 16949886

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: c22586349-22586164 mobile_element_type = transposon:INE-1{}3108
  • Loc: c22588252-22588170 mobile_element_type = transposon:INE-1{}3109
  • Loc: c22592613-22592167 mobile_element_type = transposon:INE-1{}3110
  • Loc: c22596811-22596387 mobile_element_type = transposon:INE-1{}3128
  • Loc: c22600216-22599973 mobile_element_type = transposon:INE-1{}3129
  • Loc: c22617609-22617436 mobile_element_type = transposon:INE-1{}3131

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables chitin binding IEA
Inferred from Electronic Annotation
more info
  
NOT enables chitin deacetylase activity IKR
Inferred from Key Residues
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in perivitelline space HDA PubMed 

General protein information

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Preferred Names
chitin deacetylase-like 4
Names
CG32499-PA
Cda4-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    22583634..22632710 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_167788.2 → NP_728468.1  chitin deacetylase-like 4 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728468.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VR69
    Related
    FBpp0077054
    Conserved Domains (2) summary
    cd10974
    Location:130 → 396
    CE4_CDA_like_1; Putative catalytic domain of chitin deacetylase-like proteins with additional chitin-binding peritrophin-A domain (ChBD) and/or a low-density lipoprotein receptor class A domain (LDLa)
    pfam01607
    Location:33 → 80
    CBM_14; Chitin binding Peritrophin-A domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VR69 Q9VR69

Gene LinkOut

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