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CG11562 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33200, updated on 9-Dec-2024

Summary

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Official Symbol
CG11562provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031247
Locus tag
Dmel_CG11562
See related
AllianceGenome:FB:FBgn0031247
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RE44650; Dmel\CG11562
Summary
Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be active in mitochondrion. Is expressed in adult head; anterior midgut primordium; embryonic/larval midgut; organism; and posterior midgut primordium. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 19. Orthologous to human PET117 (PET117 cytochrome c oxidase chaperone). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG11562 in Genome Data Viewer
Location:
21B7-21B7; 2-0.5 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (292419..293222)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (292419..293222)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46262 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46263 Neighboring gene amnionless Neighboring gene U2 small nuclear riboprotein auxiliary factor 38 Neighboring gene Stress induced phosphoprotein 1 Neighboring gene Pi3K21B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors. Wang L, et al. Genes Dev, 2006 Mar 1. PMID 16481466, Free PMC Article
  2. Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila. Coelho DS, et al. Cell Rep, 2013 Nov 14. PMID 24183663, Free PMC Article
  3. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Hollien J, et al. Science, 2006 Jul 7. PMID 16825573
  4. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
  5. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial cytochrome c oxidase assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial cytochrome c oxidase assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11562-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    292419..293222
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134672.2 → NP_608516.1  uncharacterized protein Dmel_CG11562 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608516.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VPN3
    Related
    FBpp0077789
    Conserved Domains (1) summary
    pfam15786
    Location:5 → 68
    PET117; PET assembly of cytochrome c oxidase, mitochondrial
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VPN3 Q9VPN3

Gene LinkOut

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