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Ent1 Equilibrative nucleoside transporter 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33207, updated on 4-Jan-2025

Summary

Official Symbol
Ent1provided by FlyBase
Official Full Name
Equilibrative nucleoside transporter 1provided by FlyBase
Primary source
FLYBASE:FBgn0031250
Locus tag
Dmel_CG11907
See related
AllianceGenome:FB:FBgn0031250
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:fe2G2; CG11907; dENT1; Dmel\CG11907; DmEnt1; DmENT1; ent1; ENT1
Summary
Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Orthologous to human SLC29A1 (solute carrier family 29 member 1 (Augustine blood group)); SLC29A2 (solute carrier family 29 member 2); and SLC29A3 (solute carrier family 29 member 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Ent1 in Genome Data Viewer
Location:
21C1-21C1; 2-0.7 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (355565..357874, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (355565..357874, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phospholipase C at 21C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45367 Neighboring gene antisense RNA:CR45366 Neighboring gene aristaless Neighboring gene long non-coding RNA:CR43718

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables nucleoside transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleoside transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleoside transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
involved_in nucleoside transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in nucleoside transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in nucleoside transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISM
Inferred from Sequence Model
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
equilibrative nucleoside transporter 1
Names
CG11907-PA
CG11907-PB
CG11907-PC
Ent1-PA
Ent1-PB
Ent1-PC
anon-fast-evolving-2G2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    355565..357874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272891.1NP_001259820.1  equilibrative nucleoside transporter 1, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259820.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95RN3, Q9NHZ1, Q9VPP0
    Conserved Domains (1) summary
    cl15430
    Location:69476
    Nucleoside_tran; Nucleoside transporter
  2. NM_134675.5NP_608519.2  equilibrative nucleoside transporter 1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608519.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95RN3, Q9NHZ1, Q9VPP0
    Related
    FBpp0077754
    Conserved Domains (1) summary
    cl15430
    Location:69476
    Nucleoside_tran; Nucleoside transporter
  3. NM_164381.2NP_722628.1  equilibrative nucleoside transporter 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722628.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95RN3, Q9NHZ1, Q9VPP0
    Related
    FBpp0077753
    Conserved Domains (1) summary
    cl15430
    Location:69476
    Nucleoside_tran; Nucleoside transporter