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shv - shriveled

Enables integrin binding activity. Involved in several processes, including germ-line stem-cell niche homeostasis; male germ-line stem cell population maintenance; and positive regulation of integrin-mediated signaling pathway. Located in extracellular space and neuromuscular junction. Is expressed in several structures, including adult head; circulatory system primordium; ganglia; male germline cell; and somatic cell of testis. Human ortholog(s) of this gene implicated in polycystic kidney disease 6. Orthologous to human DNAJB11 (DnaJ heat shock protein family (Hsp40) member B11). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa