U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG17646 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33354, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
CG17646provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0264494
Locus tag
Dmel_CG17646
See related
AllianceGenome:FB:FBgn0264494
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
ABCG1; BEST:GH05015; CG17647; DmCG17646; Dmel\CG17646; l(2)SH0142; l(2)SH2 0142
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in triglyceride metabolic process. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; brain; gut section; mushroom body extrinsic neurons; and mushroom body slice. Orthologous to human ABCG1 (ATP binding cassette subfamily G member 1) and ABCG4 (ATP binding cassette subfamily G member 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG17646 in Genome Data Viewer
Location:
22B1-22B2; 2-3 cM
Exon count:
13
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1732524..1750612)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1732524..1750612)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Enolase Neighboring gene Ribosomal RNA processing 40 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Ablation of the cholesterol transporter adenosine triphosphate-binding cassette transporter G1 reduces adipose cell size and protects against diet-induced obesity. Buchmann J, et al. Endocrinology, 2007 Apr. PMID 17194745
  2. Dissecting neural pathways for forgetting in Drosophila olfactory aversive memory. Shuai Y, et al. Proc Natl Acad Sci U S A, 2015 Dec 1. PMID 26627257, Free PMC Article
  3. Mutants of the white ABCG Transporter in Drosophila melanogaster Have Deficient Olfactory Learning and Cholesterol Homeostasis. Myers JL, et al. Int J Mol Sci, 2021 Nov 30. PMID 34884779, Free PMC Article
  4. Opposing dopaminergic and GABAergic neurons control the duration and persistence of copulation in Drosophila. Crickmore MA, et al. Cell, 2013 Nov 7. PMID 24209625, Free PMC Article
  5. Three dopamine pathways induce aversive odor memories with different stability. Aso Y, et al. PLoS Genet, 2012. PMID 22807684, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in triglyceride metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
ATP-binding cassette transporter G1
CG17646-PA
CG17646-PB
lethal (2) SH0142
NP_608618.1
NP_722727.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    1732524..1750612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164436.2 → NP_722727.1  uncharacterized protein Dmel_CG17646, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722727.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9E6, Q9VQ41, Q9VQ42
    Related
    FBpp0077553
    Conserved Domains (3) summary
    cd03213
    Location:103 → 333
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:123 → 765
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:497 → 698
    ABC2_membrane; ABC-2 type transporter

  2. NM_134774.3 → NP_608618.1  uncharacterized protein Dmel_CG17646, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608618.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9E6, Q9VQ41, Q9VQ42
    Related
    FBpp0077554
    Conserved Domains (3) summary
    cd03213
    Location:103 → 333
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:123 → 765
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:497 → 698
    ABC2_membrane; ABC-2 type transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T9E6 Q8T9E6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.