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Npc2a - Niemann-Pick type C-2a

Enables several functions, including lipopolysaccharide binding activity; lipoteichoic acid binding activity; and peptidoglycan binding activity. Involved in several processes, including positive regulation of defense response to bacterium; sterol homeostasis; and synaptic target recognition. Located in extracellular space. Is expressed in several structures, including adult heart; embryonic/larval midgut; embryonic/larval salivary gland; and ganglia. Human ortholog(s) of this gene implicated in Niemann-Pick disease and Niemann-Pick disease type C2. Orthologous to human NPC2 (NPC intracellular cholesterol transporter 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa