Rab5 - Rab5

Enables enzyme regulator activity. Involved in several processes, including endocytosis; neuron projection morphogenesis; and vesicle organization. Located in cytoplasmic vesicle; endocytic patch; and terminal bouton. Colocalizes with early endosome and presynaptic endosome. Is expressed in several structures, including adult ensheathing glial cell; brain; imaginal disc; mushroom body; and synaptic neuropil domain. Used to study cancer and carcinoma. Orthologous to several human genes including RAB5B (RAB5B, member RAS oncogene family). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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