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CG9886 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33431, updated on 4-Jan-2025

Summary

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Official Symbol
CG9886provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031428
Locus tag
Dmel_CG9886
See related
AllianceGenome:FB:FBgn0031428
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AAF51252; Dmel\CG9886
Summary
Predicted to enable glycerate kinase activity. Predicted to be involved in protein phosphorylation. Predicted to be located in cytosol and mitochondrion. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in D-glyceric aciduria. Orthologous to human GLYCTK (glycerate kinase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG9886 in Genome Data Viewer
Location:
22E1-22E1; 2-6 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2420830..2424647)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2420830..2424647)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44912

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glycerate kinase of the hyperthermophilic archaeon Thermoproteus tenax: new insights into the phylogenetic distribution and physiological role of members of the three different glycerate kinase classes. Kehrer D, et al. BMC Genomics, 2007 Aug 31. PMID 17764545, Free PMC Article
  2. The expression pattern of the Drosophila vesicular glutamate transporter: a marker protein for motoneurons and glutamatergic centers in the brain. Mahr A, et al. Gene Expr Patterns, 2006 Mar. PMID 16378756
  3. Lsd1 restricts the number of germline stem cells by regulating multiple targets in escort cells. Eliazer S, et al. PLoS Genet, 2014 Mar. PMID 24625679, Free PMC Article
  4. Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease. Huichalaf CH, et al. Hum Mol Genet, 2019 Jun 15. PMID 30753434, Free PMC Article
  5. Genomic regulatory blocks underlie extensive microsynteny conservation in insects. Engström PG, et al. Genome Res, 2007 Dec. PMID 17989259, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables glycerate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycerate kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycerate kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in protein phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9886-PA
CG9886-PB
NP_001259941.1
NP_608684.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2420830..2424647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273012.1 → NP_001259941.1  uncharacterized protein Dmel_CG9886, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259941.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VQC4
    UniProtKB/TrEMBL
    M9PB12
    Conserved Domains (3) summary
    COG2379
    Location:12 → 487
    GckA; Glycerate-2-kinase [Carbohydrate transport and metabolism]
    pfam05161
    Location:367 → 480
    MOFRL; MOFRL family
    pfam13660
    Location:10 → 261
    DUF4147; Domain of unknown function (DUF4147)

  2. NM_134840.3 → NP_608684.1  uncharacterized protein Dmel_CG9886, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608684.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VQC4
    UniProtKB/TrEMBL
    M9PB12
    Related
    FBpp0077450
    Conserved Domains (3) summary
    COG2379
    Location:12 → 487
    GckA; Glycerate-2-kinase [Carbohydrate transport and metabolism]
    pfam05161
    Location:367 → 480
    MOFRL; MOFRL family
    pfam13660
    Location:10 → 261
    DUF4147; Domain of unknown function (DUF4147)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PB12 M9PB12
Q9VQC4.1 Q9VQC4

Gene LinkOut

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