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Slh SLY-1 homologous [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33434, updated on 9-Dec-2024

Summary

Official Symbol
Slhprovided by FlyBase
Official Full Name
SLY-1 homologousprovided by FlyBase
Primary source
FLYBASE:FBgn0264978
Locus tag
Dmel_CG3539
See related
AllianceGenome:FB:FBgn0264978
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15393; CG3539; d-sly; Dmel\CG3539; slh; SLH; Sly; Sly1; SLY1; Sly1p
Old locus tag
Dmel_CG15393
Summary
Predicted to enable syntaxin binding activity. Involved in wing disc dorsal/ventral pattern formation. Predicted to be located in Golgi-associated vesicle; cis-Golgi network; and plasma membrane. Predicted to be active in Golgi membrane. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; gland; gut section; and mesoderm. Orthologous to human SCFD1 (sec1 family domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Slh in Genome Data Viewer
Location:
22F3-22F4; 2-6 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2488197..2492671, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2488197..2492671, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene transfer RNA:Tyrosine-GTA 1-3 Neighboring gene long non-coding RNA:CR45286 Neighboring gene out at first Neighboring gene long non-coding RNA:CR44607

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables SNARE binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables protein-containing complex binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables syntaxin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables syntaxin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in post-Golgi vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of ER to Golgi vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in response to hypoxia ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in response to toxic substance ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in wing disc dorsal/ventral pattern formation IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi-associated vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cis-Golgi network ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
SLY-1 homologous
Names
CG3539-PC
CG3539-PG
SLY1 homologous
Slh-PC
Slh-PG

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2488197..2492671 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001144297.2NP_001137769.2  SLY-1 homologous, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137769.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B7YZZ1, B7YZZ2, O02560, Q24179, Q4V684, Q7KU13, Q8SZB1, Q9VQC9
    Conserved Domains (1) summary
    cl15415
    Location:1630
    Sec1; Sec1 family
  2. NM_205892.2NP_995614.1  SLY-1 homologous, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995614.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B7YZZ1, B7YZZ2, O02560, Q24179, Q4V684, Q7KU13, Q8SZB1, Q9VQC9
    Conserved Domains (1) summary
    cl15415
    Location:1630
    Sec1; Sec1 family