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zdhhc18b zinc finger DHHC-type palmitoyltransferase 18b [ Danio rerio (zebrafish) ]

Gene ID: 334383, updated on 2-Nov-2024

Summary

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Official Symbol
zdhhc18bprovided by ZNC
Official Full Name
zinc finger DHHC-type palmitoyltransferase 18bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6315
See related
Ensembl:ENSDARG00000105034 AllianceGenome:ZFIN:ZDB-GENE-030131-6315
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fi45c03; zgc:55843; wu:fi45c03; wu:fj48h10
Summary
Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in negative regulation of innate immune response and protein targeting to membrane. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC18 (zinc finger DHHC-type palmitoyltransferase 18). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See zdhhc18b in Genome Data Viewer
Location:
chromosome: 19
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (14454304..14475792)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (14592292..14614704)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene T-box transcription factor Ta Neighboring gene AT-rich interactive domain 1Ab Neighboring gene centriolin-like Neighboring gene uncharacterized LOC137488434

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Protein palmitoylation activate zygotic gene expression during the maternal-to-zygotic transition. Du Z, et al. Biochem Biophys Res Commun, 2016 Jun 24. PMID 27235108
  2. Coherent but overlapping expression of microRNAs and their targets during vertebrate development. Shkumatava A, et al. Genes Dev, 2009 Feb 15. PMID 19240133, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables palmitoyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-cysteine S-palmitoyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-cysteine S-palmitoyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-cysteine S-palmitoyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of innate immune response ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
palmitoyltransferase ZDHHC18-B
Names
palmitoyltransferase ZDHHC18b
zinc finger DHHC domain-containing protein 18-B
zinc finger DHHC-type containing 18b
zinc finger, DHHC domain containing 14
NP_999872.1
XP_009292400.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214707.1 → NP_999872.1  palmitoyltransferase ZDHHC18-B

    See identical proteins and their annotated locations for NP_999872.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045475
    UniProtKB/Swiss-Prot
    Q7ZVN4
    Related
    ENSDARP00000136991.1, ENSDART00000161965.2
    Conserved Domains (1) summary
    pfam01529
    Location:161 → 285
    DHHC; DHHC palmitoyltransferase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    14454304..14475792
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009294125.4 → XP_009292400.1  palmitoyltransferase ZDHHC18-B isoform X1

    UniProtKB/TrEMBL
    A0A8M3AVE7
    Conserved Domains (1) summary
    pfam01529
    Location:161 → 285
    zf-DHHC; DHHC palmitoyltransferase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7ZVN4.1 GenPept UniProtKB/Swiss-Prot:Q7ZVN4

Gene LinkOut

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Molecular Biology Databases
Research Materials