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Trf5 TBP-related factor 5 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33454, updated on 9-Dec-2024

Summary

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Official Symbol
Trf5provided by FlyBase
Official Full Name
TBP-related factor 5provided by FlyBase
Primary source
FLYBASE:FBgn0031446
Locus tag
Dmel_CG15398
See related
AllianceGenome:FB:FBgn0031446
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15398; Dmel\CG15398; trf5
Summary
Predicted to enable RNA polymerase II general transcription initiation factor activity. Predicted to be involved in DNA-templated transcription initiation. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Trf5 in Genome Data Viewer
Location:
23A2-23A2; 2-7 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2695330..2696437, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2695330..2696437, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Gustatory receptor 23a Neighboring gene Transmembrane O-mannosyltransferase targeting cadherins 1 Neighboring gene uncharacterized protein Neighboring gene mir-4914 stem loop Neighboring gene Hepatocyte growth factor regulated tyrosine kinase substrate Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide analysis of gene regulation mechanisms during Drosophila spermatogenesis. Laktionov PP, et al. Epigenetics Chromatin, 2018 Apr 2. PMID 29609617, Free PMC Article
  2. TRF4, the novel TBP-related protein of Drosophila melanogaster, is concentrated at the endoplasmic reticulum and copurifies with proteins participating in the processes associated with endoplasmic reticulum. Kurshakova MM, et al. J Cell Biochem, 2019 May. PMID 30426565
  3. Single-cell RNA sequencing identifies eggplant as a regulator of germ cell development in Drosophila. Sun Z, et al. EMBO Rep, 2023 Oct 9. PMID 37603128, Free PMC Article
  4. A single-cell atlas reveals unanticipated cell type complexity in Drosophila ovaries. Slaidina M, et al. Genome Res, 2021 Oct. PMID 34389661, Free PMC Article
  5. The expression profile of purified Drosophila germline stem cells. Kai T, et al. Dev Biol, 2005 Jul 15. PMID 15927177

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II general transcription initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA-templated transcription initiation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
TBP-related factor 5
Names
CG15398-PB
Trf5-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2695330..2696437 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134856.3 → NP_608700.2  TBP-related factor 5 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608700.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q058R9, Q9VQE8
    Conserved Domains (2) summary
    PLN00062
    Location:110 → 265
    PLN00062; TATA-box-binding protein; Provisional
    pfam00352
    Location:191 → 267
    TBP; Transcription factor TFIID (or TATA-binding protein, TBP)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VQE8 Q9VQE8

Gene LinkOut

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