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Vmat - Vesicular monoamine transporter

Enables monoamine transmembrane transporter activity. Involved in several processes, including aminergic neurotransmitter loading into synaptic vesicle; positive regulation of dopaminergic neuron differentiation; and response to rotenone. Located in neuromuscular junction and synaptic vesicle. Is expressed in several structures, including CNS perineurial glial cell; aminergic neurons; brain; medulla layer; and synaptic neuropil domain. Human ortholog(s) of this gene implicated in Parkinson's disease; bipolar disorder; infantile parkinsonism-dystonia 2; schizophrenia; and type 1 diabetes mellitus. Orthologous to human SLC18A1 (solute carrier family 18 member A1) and SLC18A2 (solute carrier family 18 member A2). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa