rpe ribulose-5-phosphate-3-epimerase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rpeprovided by ZNC
Official Full Name: ribulose-5-phosphate-3-epimeraseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6837
See related: Ensembl:ENSDARG00000005251 AllianceGenome:ZFIN:ZDB-GENE-030131-6837
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fa07h08; wu:fb93d11; wu:fc20b11; ik:tdsubc_2c8; xx:tdsubc_2c8
Summary: Predicted to enable D-ribulose-phosphate 3-epimerase activity and metal ion binding activity. Acts upstream of or within cilium assembly. Predicted to be active in cytosol. Orthologous to human RPE (ribulose-5-phosphate-3-epimerase) and RPEL1 (ribulose-5-phosphate-3-epimerase like 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 9

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (24025509..24031461, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (24214640..24220592, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb93d11.x1 (e-PCR)
- UniSTS:203535

rpe (e-PCR), detects polymorphism
- UniSTS:205520

fc20b11.x1 (e-PCR)
- UniSTS:192976

fc20b11.x1 (e-PCR)
- UniSTS:192977

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables D-ribulose-phosphate 3-epimerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables D-ribulose-phosphate 3-epimerase activity	IEA Inferred from Electronic Annotation more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables racemase and epimerase activity, acting on carbohydrates and derivatives	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cilium assembly	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within pentose-phosphate shunt	IEA Inferred from Electronic Annotation more info
involved_in pentose-phosphate shunt, non-oxidative branch	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ribulose-phosphate 3-epimerase

NP_001230353.1

EC 5.1.3.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243424.1 → NP_001230353.1 ribulose-phosphate 3-epimerase

See identical proteins and their annotated locations for NP_001230353.1

Status: VALIDATED

Source sequence(s)

CT608262, EH574883, EH585116

UniProtKB/TrEMBL

A0A8M1NZ65, Q6PBW9

Related

ENSDARP00000023863.7, ENSDART00000021218.10

Conserved Domains (1) summary

cd00429
Location:6 → 214

RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...