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Chd1 - Chromodomain-helicase-DNA-binding protein 1

Enables chromatin binding activity. Involved in imaginal disc-derived wing morphogenesis; oogenesis; and sperm DNA decondensation. Located in polytene chromosome interband and polytene chromosome puff. Is expressed in spermatozoon. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma; developmental and epileptic encephalopathy 94; and prostate cancer. Orthologous to several human genes including CHD1 (chromodomain helicase DNA binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa