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CG17219 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33515, updated on 9-Dec-2024

Summary

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Official Symbol
CG17219provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031494
Locus tag
Dmel_CG17219
See related
AllianceGenome:FB:FBgn0031494
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG17219; METTL18
Summary
Predicted to enable protein-L-histidine N-tele-methyltransferase activity. Predicted to be involved in regulation of translation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in organism. Orthologous to human METTL18 (methyltransferase 18, RPL3 N3(tau)-histidine). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG17219 in Genome Data Viewer
Location:
23C4-23C5; 2-8 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3029253..3030616)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3029253..3030616)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene alpha1,4-galactosyltransferase 1 Neighboring gene pre-mRNA processing factor 40 Neighboring gene Splicing factor 3b subunit 2 Neighboring gene antisense RNA:CR44147 Neighboring gene beta4GalNAcTB pilot Neighboring gene uncharacterized protein Neighboring gene Seryl-tRNA synthetase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The 18S ribosomal RNA m(6) A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. Leismann J, et al. EMBO Rep, 2020 Jul 3. PMID 32350990, Free PMC Article
  2. During Drosophila disc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay. Katsuyama T, et al. Proc Natl Acad Sci U S A, 2015 May 5. PMID 25902518, Free PMC Article
  3. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
  4. Analysis of Ras-induced overproliferation in Drosophila hemocytes. Asha H, et al. Genetics, 2003 Jan. PMID 12586708, Free PMC Article
  5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein-L-histidine N-tele-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG17219-PA
NP_608740.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    3029253..3030616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134896.5 → NP_608740.2  uncharacterized protein Dmel_CG17219 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608740.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VQK8
    Related
    FBpp0077335
    Conserved Domains (1) summary
    pfam12847
    Location:141 → 261
    Methyltransf_18; Methyltransferase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SYR9 Q8SYR9
Q9VQK8 Q9VQK8

Gene LinkOut

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