MED21 Mediator complex subunit 21 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: MED21provided by FlyBase
Official Full Name: Mediator complex subunit 21provided by FlyBase
Primary source: FLYBASE:FBgn0040020
Locus tag: Dmel_CG17397
See related: AllianceGenome:FB:FBgn0040020
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG17397; CG40364; Dmel\CG17397; dSRB7; dTRAP19; med21; Med21; p18; Trap19
Summary: Enables transcription coregulator activity. Contributes to transcription coactivator activity. Involved in regulation of transcription by RNA polymerase II. Located in nucleus. Part of mediator complex. Is expressed in embryonic brain; larval ventral nerve cord; and organism. Orthologous to human MED21 (mediator complex subunit 21). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (25114924..25115946, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3LHet	NW_001848857.1 (600380..601402, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
contributes_to transcription coactivator activity	IDA Inferred from Direct Assay more info	PubMed
enables transcription coregulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables transcription coregulator activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
part_of mediator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mediator complex	IDA Inferred from Direct Assay more info	PubMed
part_of mediator complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain