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Tim23 Translocase of inner mitochondrial membrane 23 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3355096, updated on 4-Jan-2025

Summary

Official Symbol
Tim23provided by FlyBase
Official Full Name
Translocase of inner mitochondrial membrane 23provided by FlyBase
Primary source
FLYBASE:FBgn0267976
Locus tag
Dmel_CG40042
See related
AllianceGenome:FB:FBgn0267976
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:SD19278; BEST:GH02609; CG40042; Dmel\CG40042; LP07554
Summary
Predicted to enable protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is expressed in adult head; adult heart; and organism. Orthologous to human TIMM23 (translocase of inner mitochondrial membrane 23) and TIMM23B (translocase of inner mitochondrial membrane 23 homolog B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Tim23 in Genome Data Viewer
Location:
40F7-40F7; 2-54 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (23312465..23313578, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2LHet NW_001848855.1 (167980..169093, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46253 Neighboring gene Glycoprotein hormone beta 5 Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

  • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein import into mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
translocase of inner mitochondrial membrane 23
Names
CG40042-PA
Tim23-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    23312465..23313578 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001015387.3NP_001015387.1  translocase of inner mitochondrial membrane 23 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001015387.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MRW1
    Conserved Domains (1) summary
    cl02381
    Location:42188
    Tim17; Tim17/Tim22/Tim23/Pmp24 family