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scro - scarecrow

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in dendrite morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including adult optic lobe; anterior ectoderm derivative; clypeo-labral anlage; embryonic epipharynx; and ganglia. Human ortholog(s) of this gene implicated in choreatic disease and papillary thyroid carcinoma. Orthologous to several human genes including NKX2-4 (NK2 homeobox 4). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa