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dnaja3a DnaJ heat shock protein family (Hsp40) member A3a [ Danio rerio (zebrafish) ]

Gene ID: 335894, updated on 4-Jan-2025

Summary

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Official Symbol
dnaja3aprovided by ZNC
Official Full Name
DnaJ heat shock protein family (Hsp40) member A3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7837
See related
Ensembl:ENSDARG00000058494 AllianceGenome:ZFIN:ZDB-GENE-030131-7837
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fj36c02
Summary
Predicted to enable several functions, including ATP binding activity; heat shock protein binding activity; and unfolded protein binding activity. Predicted to act upstream of or within protein folding and response to heat. Orthologous to human DNAJA3 (DnaJ heat shock protein family (Hsp40) member A3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See dnaja3a in Genome Data Viewer
Location:
chromosome: 3
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (11926070..11947672)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (11985831..12007472)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene forkhead box K2b Neighboring gene coronin-7-like Neighboring gene heme oxygenase 2b Neighboring gene cilia and flagella associated protein 70

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Selection of reliable biomarkers from PCR array analyses using relative distance computational model: methodology and proof-of-concept study. Liu C, et al. PLoS One, 2013. PMID 24349563, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables heat shock protein binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein folding IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to heat IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DnaJ heat shock protein family (Hsp40) member A3a; dnaJ heat shock protein family (Hsp40) member A3a
Names
DnaJ (Hsp40) homolog, subfamily A, member 3A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201313.1 → NP_958470.1  DnaJ heat shock protein family (Hsp40) member A3a

    See identical proteins and their annotated locations for NP_958470.1

    Status: PROVISIONAL

    Source sequence(s)
    BC047809
    UniProtKB/TrEMBL
    B2GT20, Q7ZUW0
    Related
    ENSDARP00000075810.4, ENSDART00000081367.5
    Conserved Domains (4) summary
    cd10719
    Location:236 → 296
    DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    cd10747
    Location:207 → 416
    DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
    COG0484
    Location:89 → 435
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    pfam00226
    Location:91 → 153
    DnaJ; DnaJ domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    11926070..11947672
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005168471.5 → XP_005168528.1  dnaJ heat shock protein family (Hsp40) member A3a isoform X1

    UniProtKB/TrEMBL
    A0A8M2BFS1
    Conserved Domains (4) summary
    cd10719
    Location:236 → 296
    DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    cd10747
    Location:207 → 416
    DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
    COG0484
    Location:89 → 474
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
    pfam00226
    Location:91 → 153
    DnaJ; DnaJ domain

RNA

  1. XR_011007989.1 RNA Sequence

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394520.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    59528..81094
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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