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CG2818 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33597, updated on 9-Dec-2024

Summary

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Official Symbol
CG2818provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031566
Locus tag
Dmel_CG2818
See related
AllianceGenome:FB:FBgn0031566
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2818
Summary
Predicted to enable glycerophosphocholine phosphodiesterase activity. Predicted to be involved in glycerophospholipid catabolic process. Is expressed in several structures, including dorsal ectoderm; dorsal head epidermis anlage; embryonic head epidermis; embryonic head sensory system; and hindgut anlage. Orthologous to human GPCPD1 (glycerophosphocholine phosphodiesterase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG2818 in Genome Data Viewer
Location:
24C1-24C1; 2-11 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3713360..3716810)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3713360..3716810)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene cutlet Neighboring gene uncharacterized protein Neighboring gene lectin-24A Neighboring gene Shaker cognate w Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
  2. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
  3. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
  4. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
  5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables glycerophosphocholine phosphodiesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphoric diester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables starch binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glycerophospholipid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2818-PA
CG2818-PB
NP_608804.1
NP_722936.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    3713360..3716810
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134960.4 → NP_608804.1  uncharacterized protein Dmel_CG2818, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608804.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T074, Q9VQU3
    Related
    FBpp0077226
    Conserved Domains (3) summary
    cd05814
    Location:44 → 166
    CBM20_Prei4; Prei4, N-terminal CBM20 (carbohydrate-binding module, family 20) domain. Preimplantation protein 4 (Prei4) is a protein of unknown function that is expressed during mouse preimplantation embryogenesis. In addition to the N-terminal CBM20 domain, Prei4 ...
    cd08607
    Location:371 → 659
    GDPD_GDE5; Glycerophosphodiester phosphodiesterase domain of putative mammalian glycerophosphodiester phosphodiesterase GDE5 and similar proteins
    pfam03009
    Location:375 → 661
    GDPD; Glycerophosphoryl diester phosphodiesterase family

  2. NM_164553.2 → NP_722936.1  uncharacterized protein Dmel_CG2818, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722936.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IQ03
    Related
    FBpp0077227
    Conserved Domains (2) summary
    cd08607
    Location:185 → 473
    GDPD_GDE5; Glycerophosphodiester phosphodiesterase domain of putative mammalian glycerophosphodiester phosphodiesterase GDE5 and similar proteins
    pfam03009
    Location:189 → 475
    GDPD; Glycerophosphoryl diester phosphodiesterase family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IQ03 Q8IQ03
Q9VQU3 Q9VQU3

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