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CG17612 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33639, updated on 4-Jan-2025

Summary

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Official Symbol
CG17612provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031597
Locus tag
Dmel_CG17612
See related
AllianceGenome:FB:FBgn0031597
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG17612
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in embryonic brain; larval ventral nerve cord; and organism. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG17612 in Genome Data Viewer
Location:
24E4-24E4; 2-12 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4380722..4382735, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4380722..4382735, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45363 Neighboring gene TNF-receptor-associated factor 4 Neighboring gene Vacuolar protein sorting 53 Neighboring gene Partner of Sld Five 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila homologs of mammalian TNF/TNFR-related molecules regulate segregation of Miranda/Prospero in neuroblasts. Wang H, et al. EMBO J, 2006 Dec 13. PMID 17139248, Free PMC Article
  2. A link between impaired purine nucleotide synthesis and apoptosis in Drosophila melanogaster. Holland C, et al. Genetics, 2011 Jun. PMID 21441212, Free PMC Article
  3. High resolution mapping of Twist to DNA in Drosophila embryos: Efficient functional analysis and evolutionary conservation. Ozdemir A, et al. Genome Res, 2011 Apr. PMID 21383317, Free PMC Article
  4. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
  5. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription cis-regulatory region binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG17612-PA
CG17612-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4380722..4382735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164581.2 → NP_722973.1  uncharacterized protein Dmel_CG17612, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722973.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    I0E2I7, Q9VQY7
    Related
    FBpp0077152
    Conserved Domains (4) summary
    sd00017
    Location:359 → 379
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:323 → 343
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07776
    Location:187 → 246
    zf-AD; Zinc-finger associated domain (zf-AD)
    pfam15909
    Location:356 → 438
    zf-C2H2_8; C2H2-type zinc ribbon

  2. NM_134980.2 → NP_608824.1  uncharacterized protein Dmel_CG17612, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608824.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    I0E2I7, Q9VQY7
    Related
    FBpp0077153
    Conserved Domains (4) summary
    sd00017
    Location:359 → 379
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:323 → 343
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07776
    Location:187 → 246
    zf-AD; Zinc-finger associated domain (zf-AD)
    pfam15909
    Location:356 → 438
    zf-C2H2_8; C2H2-type zinc ribbon
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VQY7 Q9VQY7

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