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Secp43 tRNA Selenocysteine associated protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33652, updated on 4-Jan-2025

Summary

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Official Symbol
Secp43provided by FlyBase
Official Full Name
tRNA Selenocysteine associated proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031607
Locus tag
Dmel_CG15440
See related
AllianceGenome:FB:FBgn0031607
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg15440; CG15440; Dmel\CG15440
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to be active in cytosol. Orthologous to human TRNAU1AP (tRNA selenocysteine 1 associated protein 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Secp43 in Genome Data Viewer
Location:
24F3-24F3; 2-12 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4453169..4454453, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4453169..4454453, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Elongator complex protein 3 Neighboring gene Major Facilitator Superfamily Transporter 18 Neighboring gene uncharacterized protein Neighboring gene NADH dehydrogenase (ubiquinone) B8 subunit Neighboring gene ncRNA Neighboring gene GS1-like Neighboring gene Ribosomal protein L27A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Relaxation of selective constraints causes independent selenoprotein extinction in insect genomes. Chapple CE, et al. PLoS One, 2008 Aug 13. PMID 18698431, Free PMC Article
  2. mTORC1-chaperonin CCT signaling regulates m(6)A RNA methylation to suppress autophagy. Tang HW, et al. Proc Natl Acad Sci U S A, 2021 Mar 9. PMID 33649236, Free PMC Article
  3. spenito is required for sex determination in Drosophila melanogaster. Yan D, et al. Proc Natl Acad Sci U S A, 2015 Sep 15. PMID 26324914, Free PMC Article
  4. The drosophila melanogaster genome: translation factors and RNA binding proteins. Lasko P. J Cell Biol, 2000 Jul 24. PMID 10908586, Free PMC Article
  5. Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis. Lin WH, et al. Dis Model Mech, 2017 Feb 1. PMID 28067623, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mRNA splice site recognition IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tRNA selenocysteine associated protein
Names
CG15440-PA
Secp43-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4453169..4454453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134993.2 → NP_608837.2  tRNA selenocysteine associated protein [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608837.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SXG7, Q9VQZ9
    Related
    FBpp0077144
    Conserved Domains (2) summary
    cd12610
    Location:7 → 90
    RRM1_SECp43; RNA recognition motif 1 in tRNA selenocysteine-associated protein 1 (SECp43)
    cd12612
    Location:99 → 180
    RRM2_SECp43; RNA recognition motif 2 in tRNA selenocysteine-associated protein 1 (SECp43)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SXG7 Q8SXG7

Gene LinkOut

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