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slf schlaff [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33678, updated on 9-Dec-2024

Summary

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Official Symbol
slfprovided by FlyBase
Official Full Name
schlaffprovided by FlyBase
Primary source
FLYBASE:FBgn0287234
Locus tag
Dmel_CG3244
See related
AllianceGenome:FB:FBgn0287234
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3244; Clect27; Dmel\CG3244; l(2)25Aa; Slf
Summary
Predicted to enable carbohydrate binding activity. Is expressed in adult head; embryonic dorsal epidermis; embryonic head epidermis; and embryonic ventral epidermis. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See slf in Genome Data Viewer
Location:
25A6-25A6; 2-13 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4796600..4801923, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4796600..4801923, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene factor of interpulse interval Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45297 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pluripotency and a secretion mechanism of Drosophila transglutaminase. Shibata T, et al. J Biochem, 2018 Mar 1. PMID 28992227
  2. Blastoderm-differential and blastoderm-specific genes of Drosophila melanogaster. Roark M, et al. Dev Biol, 1985 Jun. PMID 2581833
  3. The putative C-type lectin Schlaff ensures epidermal barrier compactness in Drosophila. Zuber R, et al. Sci Rep, 2019 Mar 29. PMID 30926832, Free PMC Article
  4. Protein crosslinking by transglutaminase controls cuticle morphogenesis in Drosophila. Shibata T, et al. PLoS One, 2010 Oct 18. PMID 20976106, Free PMC Article
  5. Form and function of the apical extracellular matrix: new insights from Caenorhabditis elegans, Drosophila melanogaster, and the vertebrate inner ear. Li Zheng S, et al. Fac Rev, 2020. PMID 33659959, Free PMC Article

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbohydrate binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
schlaff
Names
C-type lectin 27kD
CG3244-PA
CG3244-PB
slf-PA
slf-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4796600..4801923 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135014.3 → NP_608858.3  schlaff, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608858.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZK9, Q9VR27
    Related
    FBpp0077108
    Conserved Domains (1) summary
    cd00037
    Location:67 → 213
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

  2. NM_001273117.1 → NP_001260046.1  schlaff, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260046.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZK9, Q9VR27
    Conserved Domains (1) summary
    cd00037
    Location:67 → 213
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SZK9 Q8SZK9

Gene LinkOut

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