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CG3008 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33693, updated on 4-Jan-2025

Summary

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Official Symbol
CG3008provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031643
Locus tag
Dmel_CG3008
See related
AllianceGenome:FB:FBgn0031643
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3008
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in cytoplasm and nucleus. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut; embryonic/larval midgut primordium; ganglia; and germline cell. Orthologous to human RIOK3 (RIO kinase 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG3008 in Genome Data Viewer
Location:
25B1-25B1; 2-14 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4883298..4885669)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4883298..4885669)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene smog Neighboring gene Chorion factor 2 Neighboring gene uncharacterized protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Piwi interacts with chromatin at nuclear pores and promiscuously binds nuclear transcripts in Drosophila ovarian somatic cells. Ilyin AA, et al. Nucleic Acids Res, 2017 Jul 27. PMID 28472469, Free PMC Article
  2. Classification and functional annotation of eukaryotic protein kinases. Miranda-Saavedra D, et al. Proteins, 2007 Sep 1. PMID 17557329
  3. Quantitative proteomic analysis of protein complexes: concurrent identification of interactors and their state of phosphorylation. Pflieger D, et al. Mol Cell Proteomics, 2008 Feb. PMID 17956857
  4. New comparative genomics approach reveals a conserved health span signature across species. Antosh M, et al. Aging (Albany NY), 2011 Jun. PMID 21775776, Free PMC Article
  5. The Spalt Transcription Factors Generate the Transcriptional Landscape of the Drosophila melanogaster Wing Pouch Central Region. Organista MF, et al. PLoS Genet, 2015 Aug. PMID 26241320, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of preribosome, small subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3008-PA
NP_608871.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4883298..4885669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135027.4 → NP_608871.1  uncharacterized protein Dmel_CG3008 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608871.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VR42
    Related
    FBpp0077081
    Conserved Domains (2) summary
    COG1718
    Location:242 → 505
    RIO1; Serine/threonine-protein kinase RIO1 [Signal transduction mechanisms]
    cd05146
    Location:278 → 488
    RIO3_euk; Catalytic domain of the atypical protein serine kinase, RIO3 kinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VR42 Q9VR42

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