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mpx - myeloid-specific peroxidase

Enables peroxidase activity. Acts upstream of or within inflammatory response; regulation of hydrogen peroxide metabolic process; and response to bacterium. Located in cytoplasm. Is expressed in several structures, including digestive system; hematopoietic cell; hematopoietic system; mesoderm; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; cystic fibrosis; kidney failure (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to several human genes including EPX (eosinophil peroxidase). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa