scarb2c scavenger receptor class B, member 2c [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: scarb2cprovided by ZNC
Official Full Name: scavenger receptor class B, member 2cprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5789
See related: AllianceGenome:ZFIN:ZDB-GENE-030131-5789
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fi18e02; fj81e10; wu:fi18e02; wu:fj81e10
Summary: Predicted to enable scavenger receptor activity. Predicted to be located in lysosome and membrane. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 4. Orthologous to human SCARB2 (scavenger receptor class B member 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (974445..1009150)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (733616..767468, complement)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables scavenger receptor activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: lysosome membrane protein 2c

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001365142.1 → NP_001352071.1 lysosome membrane protein 2c

Status: VALIDATED

Source sequence(s)

CABZ01057159, LO018018

UniProtKB/TrEMBL

A0A8M9PU63

Conserved Domains (1) summary

pfam01130
Location:15 → 457

CD36; CD36 family