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Bub1 - Bub1 kinase

Predicted to enable protein kinase activity. Involved in mitotic spindle assembly checkpoint signaling. Located in centrosome. Is expressed in organism and primordial germ cell. Human ortholog(s) of this gene implicated in colorectal cancer and primary autosomal recessive microcephaly. Orthologous to human BUB1 (BUB1 mitotic checkpoint serine/threonine kinase). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa