Cox11 Cytochrome c oxidase copper chaperone COX11 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Cox11provided by FlyBase
Official Full Name: Cytochrome c oxidase copper chaperone COX11provided by FlyBase
Primary source: FLYBASE:FBgn0051648
Locus tag: Dmel_CG31648
See related: AllianceGenome:FB:FBgn0051648
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG31648; CG6922; COXZ; Dmel\CG31648
Summary: Predicted to enable copper ion binding activity. Predicted to be involved in aerobic respiration and protein-containing complex assembly. Predicted to be located in mitochondrial envelope. Predicted to be active in mitochondrial inner membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 23. Orthologous to human COX11 (cytochrome c oxidase copper chaperone COX11). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (5526957..5527854)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (5526957..5527854)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables copper ion binding	IEA Inferred from Electronic Annotation more info
enables copper ion binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in aerobic respiration	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein-containing complex assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in mitochondrial envelope	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info

Names: CG31648-PA; Cox11-PA; complex IV assembly protein COX11; cytochrome c oxidase assembly protein COX11

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The following sections contain reference sequences that belong to a specific genome build. Explain