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Vm26Ab Vitelline membrane 26Ab [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33827, updated on 4-Jan-2025

Summary

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Official Symbol
Vm26Abprovided by FlyBase
Official Full Name
Vitelline membrane 26Abprovided by FlyBase
Primary source
FLYBASE:FBgn0003980
Locus tag
Dmel_CG9046
See related
AllianceGenome:FB:FBgn0003980
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9046; DIM 29; Dm sV23; Dmel\CG9046; fs(2)QJ42; sv23; sV23; Sv23; sV26; TU-4; Vm26A; VM26A.2; VM26AB
Summary
Involved in egg activation and vitelline membrane formation involved in chorion-containing eggshell formation. Located in vitelline envelope. Is expressed in follicle cell; main body follicle cell; and vitelline membrane. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Vm26Ab in Genome Data Viewer
Location:
26A3-26A3; 2-18 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5957004..5957639)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5957004..5957639)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Vitelline membrane 26Aac Neighboring gene Vitelline membrane 26Aa

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular analysis and rescue of a vitelline membrane mutant in Drosophila. Savant SS, et al. Dev Biol, 1989 Sep. PMID 2504634
  2. Isolation of two Drosophila melanogaster genes abundantly expressed in the ovary during vitelline membrane synthesis. Higgins MJ, et al. Dev Biol, 1984 Sep. PMID 6088330
  3. Ovulation triggers activation of Drosophila oocytes. Heifetz Y, et al. Dev Biol, 2001 Jun 15. PMID 11397010
  4. The Drosophila drop-dead gene is required for eggshell integrity. Sheahan TD, et al. PLoS One, 2023. PMID 38051756, Free PMC Article
  5. Characterization and sequence of follicle cell genes selectively expressed during vitelline membrane formation in Drosophila. Burke T, et al. Dev Biol, 1987 Dec. PMID 3119397

See all (67) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in chorion-containing eggshell formation HMP PubMed 
involved_in egg activation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to bacterium HEP PubMed 
involved_in vitelline membrane formation involved in chorion-containing eggshell formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in vitelline envelope IDA
Inferred from Direct Assay
more info
 PubMed 
located_in vitelline envelope IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
vitelline membrane 26Ab
Names
CG9046-PA
CG9046-PB
Vm26Ab-PA
Vm26Ab-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    5957004..5957639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298719.1 → NP_001285648.1  vitelline membrane 26Ab, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285648.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4UM08, P13238, Q9VMK6
    UniProtKB/TrEMBL
    A8E794, X2J4V0
    Conserved Domains (1) summary
    pfam10542
    Location:118 → 154
    Vitelline_membr; Vitelline membrane cysteine-rich region

  2. NM_057436.2 → NP_476784.1  vitelline membrane 26Ab, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476784.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4UM08, P13238, Q9VMK6
    UniProtKB/TrEMBL
    A8E794, X2J4V0
    Related
    FBpp0078802, FBtr0079171
    Conserved Domains (1) summary
    pfam10542
    Location:118 → 154
    Vitelline_membr; Vitelline membrane cysteine-rich region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P13238.2 P13238
X2J4V0 X2J4V0

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