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Acad12 acyl-Coenzyme A dehydrogenase family, member 12 [ Mus musculus (house mouse) ]

Gene ID: 338350, updated on 27-Nov-2024

Summary

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Official Symbol
Acad12provided by MGI
Official Full Name
acyl-Coenzyme A dehydrogenase family, member 12provided by MGI
Primary source
MGI:MGI:2443320
See related
Ensembl:ENSMUSG00000042647 AllianceGenome:MGI:2443320
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9330129D05Rik
Summary
Predicted to enable acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Located in mitochondrion. Orthologous to human ACAD10 (acyl-CoA dehydrogenase family member 10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in heart adult (RPKM 19.6), kidney adult (RPKM 16.2) and 17 other tissues See more
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Genomic context

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See Acad12 in Genome Data Viewer
Location:
5 F; 5 61.87 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (121736340..121757001, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (121598277..121618938, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_14259 Neighboring gene MAP kinase-activated protein kinase 5 Neighboring gene STARR-positive B cell enhancer ABC_E9092 Neighboring gene STARR-positive B cell enhancer ABC_E11301 Neighboring gene STARR-seq mESC enhancer starr_14260 Neighboring gene aldehyde dehydrogenase 2, mitochondrial Neighboring gene STARR-seq mESC enhancer starr_14261 Neighboring gene acyl-Coenzyme A dehydrogenase family, member 10 Neighboring gene BRCA1 associated protein Neighboring gene ataxin 2 Neighboring gene STARR-seq mESC enhancer starr_14264 Neighboring gene SH2B adaptor protein 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome. Grose JH, et al. PLoS One, 2015. PMID 26465331, Free PMC Article
  2. The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes. Liu F, et al. Mol Cell Proteomics, 2018 Feb. PMID 29222160, Free PMC Article
  3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acyl-CoA dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
acyl-Coenzyme A dehydrogenase family, member 10-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178799.3 → NP_848914.2  acyl-Coenzyme A dehydrogenase family, member 10-like

    See identical proteins and their annotated locations for NP_848914.2

    Status: VALIDATED

    Source sequence(s)
    AK033963, AK080793, BB352084, BB643798
    Consensus CDS
    CCDS51642.1
    UniProtKB/TrEMBL
    D3Z7X0
    Related
    ENSMUSP00000046497.7, ENSMUST00000041252.13
    Conserved Domains (2) summary
    TIGR02247
    Location:41 → 58
    HAD-1A3-hyp; epoxide hydrolase N-terminal domain-like phosphatase
    cl09933
    Location:154 → 542
    ACAD; Acyl-CoA dehydrogenase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    121736340..121757001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248231.1 → XP_011246533.1  acyl-Coenzyme A dehydrogenase family, member 10-like isoform X1

    See identical proteins and their annotated locations for XP_011246533.1

    UniProtKB/TrEMBL
    D3Z7X0
    Conserved Domains (2) summary
    TIGR02247
    Location:41 → 58
    HAD-1A3-hyp; epoxide hydrolase N-terminal domain-like phosphatase
    cl09933
    Location:154 → 542
    ACAD; Acyl-CoA dehydrogenase
Nucleotide Protein Strain
Heading Accession and Version

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