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CG9135 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33850, updated on 9-Dec-2024

Summary

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Official Symbol
CG9135provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031769
Locus tag
Dmel_CG9135
See related
AllianceGenome:FB:FBgn0031769
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9135
Summary
Predicted to enable small GTPase binding activity. Predicted to be involved in chromosome passenger complex localization to kinetochore and positive regulation of attachment of spindle microtubules to kinetochore. Predicted to be active in membrane. Is expressed in several structures, including antennal primordium; anterior endoderm anlage; ganglia; head epidermis primordium; and sensory nervous system primordium. Orthologous to human RCC2 (regulator of chromosome condensation 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG9135 in Genome Data Viewer
Location:
26B3-26B3; 2-18 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6050800..6053877)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6050800..6053877)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phosphoribosylformylglycinamidine synthase Neighboring gene mir-966 stem loop Neighboring gene uncharacterized protein Neighboring gene slowmo Neighboring gene Inositol phosphatase interacting protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene NADH dehydrogenase (ubiquinone) 51 kDa subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic variation in a member of the laminin gene family affects variation in body composition in Drosophila and humans. De Luca M, et al. BMC Genet, 2008 Aug 11. PMID 18694491, Free PMC Article
  2. Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing. Schübeler D, et al. Nat Genet, 2002 Nov. PMID 12355067
  3. Variant histone H3.3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias. Wirbelauer C, et al. Genes Dev, 2005 Aug 1. PMID 16077006, Free PMC Article
  4. Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila. Bell O, et al. EMBO J, 2007 Dec 12. PMID 18007591, Free PMC Article
  5. Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library- Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene. Kumar S, et al. Sci Rep, 2016 Nov 7. PMID 27819340, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables small GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chromosome passenger complex localization to kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of attachment of spindle microtubules to kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9135-PA
CG9135-PB
CG9135-PC
CG9135-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    6050800..6053877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298727.1 → NP_001285656.1  uncharacterized protein Dmel_CG9135, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285656.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VMI5
    Conserved Domains (2) summary
    pfam00415
    Location:317 → 366
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam13540
    Location:171 → 200
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat

  2. NM_001298726.1 → NP_001285655.1  uncharacterized protein Dmel_CG9135, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285655.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VMI5
    Conserved Domains (2) summary
    pfam00415
    Location:317 → 366
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam13540
    Location:171 → 200
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat

  3. NM_164679.2 → NP_723150.1  uncharacterized protein Dmel_CG9135, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723150.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VMI5
    Related
    FBpp0078817
    Conserved Domains (2) summary
    pfam00415
    Location:317 → 366
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam13540
    Location:171 → 200
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat

  4. NM_135141.3 → NP_608985.1  uncharacterized protein Dmel_CG9135, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608985.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VMI5
    Related
    FBpp0078816
    Conserved Domains (2) summary
    pfam00415
    Location:317 → 366
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam13540
    Location:171 → 200
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VMI5 Q9VMI5

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