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homer - homer

Predicted to enable G protein-coupled glutamate receptor binding activity. Involved in behavioral response to ethanol; positive regulation of circadian sleep/wake cycle, sleep; and regulation of locomotion. Located in dendrite and endoplasmic reticulum. Is expressed in several structures, including brain; central nervous system; embryonic/larval midgut primordium; head epidermis primordium; and synaptic neuropil domain. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 68. Orthologous to several human genes including HOMER2 (homer scaffold protein 2) and HOMER3 (homer scaffold protein 3). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa