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snRNP-U1-70K - small ribonucleoprotein particle U1 subunit 70K

Enables mRNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome; oogenesis; and spermatogenesis. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in several structures, including central brain primordium; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; ganglia; and mesoderm. Human ortholog(s) of this gene implicated in disease of mental health and systemic lupus erythematosus. Orthologous to human SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to snRNP-U1-70K

NCBI Orthologs

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Species Gene Architecture aa