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Pcp Pupal cuticle protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33985, updated on 9-Dec-2024

Summary

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Official Symbol
Pcpprovided by FlyBase
Official Full Name
Pupal cuticle proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0003046
Locus tag
Dmel_CG3440
See related
AllianceGenome:FB:FBgn0003046
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3440; DMCPGART; DmelPcp; Dmel\CG3440; Gart; PCP-Gart; Pcpgart
Summary
Predicted to be a structural constituent of chitin-based larval cuticle and structural constituent of pupal chitin-based cuticle. Involved in imaginal disc fusion, thorax closure. Predicted to be active in chitin-based extracellular matrix. Is expressed in larval abdomen. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Pcp in Genome Data Viewer
Location:
27D4-27D4; 2-24 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7021682..7022470)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7021682..7022470)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene GART trifunctional enzyme Neighboring gene uncharacterized protein Neighboring gene Mitochondrial Magnesium Exporter 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unusual organizational features of the Drosophila Gart locus are not conserved within Diptera. Clark DV, et al. J Mol Evol, 1992 Jul. PMID 1518084
  2. Gene within a gene: nested Drosophila genes encode unrelated proteins on opposite DNA strands. Henikoff S, et al. Cell, 1986 Jan 17. PMID 3079672
  3. Conserved arrangement of nested genes at the Drosophila Gart locus. Henikoff S, et al. Genetics, 1987 Dec. PMID 3123310, Free PMC Article
  4. The cuticle genes of drosophila: a developmentally regulated gene cluster. Snyder M, et al. Cell, 1981 Jul. PMID 6168386
  5. Broad specifies pupal development and mediates the 'status quo' action of juvenile hormone on the pupal-adult transformation in Drosophila and Manduca. Zhou X, et al. Development, 2002 May. PMID 11959833

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of chitin-based larval cuticle IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of chitin-based larval cuticle ISM
Inferred from Sequence Model
more info
 PubMed 
enables structural constituent of pupal chitin-based cuticle ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables structural constituent of pupal chitin-based cuticle TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in chitin-based cuticle development ISM
Inferred from Sequence Model
more info
 PubMed 
involved_in imaginal disc fusion, thorax closure IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chitin-based extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chitin-based extracellular matrix ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
pupal cuticle protein
Names
CG3440-PA
Pcp-PA
gart intron gene
gart intronic gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7021682..7022470
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_057325.3 → NP_476673.1  pupal cuticle protein [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476673.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8WHK2, P14484, Q9VM52
    Related
    FBpp0079016
    Conserved Domains (1) summary
    pfam00379
    Location:45 → 92
    Chitin_bind_4; Insect cuticle protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P14484.1 P14484

Gene LinkOut

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