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CG5149 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34013, updated on 4-Jan-2025

Summary

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Official Symbol
CG5149provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031904
Locus tag
Dmel_CG5149
See related
AllianceGenome:FB:FBgn0031904
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5149
Summary
Predicted to be involved in response to oxidative stress. Predicted to be active in nucleus. Is expressed in several structures, including adult head; amnioserosa; embryonic central brain neurons; ganglia; and larval glial cell. Orthologous to human MEAK7 (MTOR associated protein, eak-7 homolog). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG5149 in Genome Data Viewer
Location:
27F3-27F3; 2-26 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7384486..7388253, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7384486..7388253, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Wnt oncogene analog 10 Neighboring gene antisense RNA:CR44063 Neighboring gene neither inactivation nor afterpotential C Neighboring gene gudu Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Doublesex controls specification and maintenance of the gonad stem cell niches in Drosophila. Camara N, et al. Development, 2019 Jun 10. PMID 31043421, Free PMC Article
  2. The establishment of sexual identity in the Drosophila germline. Casper AL, et al. Development, 2009 Nov. PMID 19855024, Free PMC Article
  3. Germline masculinization by Phf7 in D. melanogaster requires its evolutionarily novel C-terminus and the HP1-family protein HP1D3csd. Yang SY. Sci Rep, 2021 Mar 18. PMID 33737548, Free PMC Article
  4. Organization and regulation of sex-specific thioredoxin encoding genes in the genus Drosophila. Svensson MJ, et al. Dev Genes Evol, 2007 Sep. PMID 17701050
  5. Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. Page AR, et al. EMBO J, 2005 Dec 21. PMID 16369566, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5149-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7384486..7388253 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135266.4 → NP_609110.1  uncharacterized protein Dmel_CG5149 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609110.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VM22
    Related
    FBpp0079093
    Conserved Domains (2) summary
    smart00584
    Location:232 → 400
    TLDc; domain in TBC and LysM domain containing proteins
    pfam16779
    Location:11 → 67
    DMP12; DNA-mimic protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VM22 Q9VM22

Gene LinkOut

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