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CG15818 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34019, updated on 9-Dec-2024

Summary

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Official Symbol
CG15818provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031910
Locus tag
Dmel_CG15818
See related
AllianceGenome:FB:FBgn0031910
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG15818
Summary
Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be located in extracellular region. Predicted to be active in external side of plasma membrane. Is expressed in embryonic proventriculus and embryonic/larval midgut. Human ortholog(s) of this gene implicated in 3MC syndrome 3; asthma; lung disease (multiple); respiratory syncytial virus infectious disease; and rhinitis. Orthologous to several human genes including COLEC10 (collectin subfamily member 10); SFTPA1 (surfactant protein A1); and SFTPA2 (surfactant protein A2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG15818 in Genome Data Viewer
Location:
27F3-27F3; 2-26 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7410909..7412229)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7410909..7412229)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46205 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene chameau Neighboring gene long non-coding RNA:CR43857 Neighboring gene mir-275 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An endogenous Drosophila receptor for glycans bearing alpha 1,3-linked core fucose residues. Bouyain S, et al. J Biol Chem, 2002 Jun 21. PMID 11960993
  2. Evidence of spatially varying selection acting on four chromatin-remodeling loci in Drosophila melanogaster. Levine MT, et al. Genetics, 2008 May. PMID 18245821, Free PMC Article
  3. A genome-wide scan for genes under balancing selection in Drosophila melanogaster. Croze M, et al. BMC Evol Biol, 2017 Jan 13. PMID 28086750, Free PMC Article
  4. Molecular evolution and population genetics of duplicated accessory gland protein genes in Drosophila. Holloway AK, et al. Mol Biol Evol, 2004 Sep. PMID 15215320
  5. High fat diet induces sex-specific differential gene expression in Drosophila melanogaster. Stobdan T, et al. PLoS One, 2019. PMID 30861021, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbohydrate binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables pattern recognition receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG15818-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7410909..7412229
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135272.4 → NP_609116.1  uncharacterized protein Dmel_CG15818 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609116.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VM16
    Related
    FBpp0079070
    Conserved Domains (1) summary
    cd00037
    Location:164 → 278
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VM16 Q9VM16

Gene LinkOut

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