Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search NCBI

LKRSDH - Lysine ketoglutarate reductase/saccharopine dehydrogenase

Enables several functions, including nuclear receptor binding activity; saccharopine dehydrogenase (NAD+, L-lysine-forming) activity; and transcription corepressor activity. Involved in lysine catabolic process; negative regulation of ecdysone receptor signaling pathway; and negative regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. Is expressed in adult head; adult heart; and salivary gland. Human ortholog(s) of this gene implicated in hyperlysinemia. Orthologous to human AASS (aminoadipate-semialdehyde synthase). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to LKRSDH

NCBI Orthologs

How was this calculated?

genes for:

Protein alignment

Align

Download data

Download
Species Gene Architecture aa