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CG7115 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34069, updated on 9-Dec-2024

Summary

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Official Symbol
CG7115provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0027515
Locus tag
Dmel_CG7115
See related
AllianceGenome:FB:FBgn0027515
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:LD21794; Dmel\CG7115; dPPM1L; PP2C
Summary
Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including adult head; germline cell; larval muscle system; and pole plasm. Orthologous to human PPM1L (protein phosphatase, Mg2+/Mn2+ dependent 1L). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG7115 in Genome Data Viewer
Location:
28D1-28D1; 2-29 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7821151..7825350)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7821151..7825350)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene r2d2 Neighboring gene Cell division cycle 14 Neighboring gene LanB1 Neighboring gene antisense RNA:CR45008 Neighboring gene Receptor of activated protein kinase C 1 Neighboring gene microtubule star Neighboring gene pseudo

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Kinome RNAi Screen in Drosophila Identifies Novel Genes Interacting with Lgl, aPKC, and Crb Cell Polarity Genes in Epithelial Tissues. Parsons LM, et al. G3 (Bethesda), 2017 Aug 7. PMID 28611255, Free PMC Article
  2. An RNAi Screen To Identify Protein Phosphatases That Function Within the Drosophila Circadian Clock. Agrawal P, et al. G3 (Bethesda), 2016 Dec 7. PMID 27784754, Free PMC Article
  3. Genome-wide RNAi screen identifies broadly-acting host factors that inhibit arbovirus infection. Yasunaga A, et al. PLoS Pathog, 2014 Feb. PMID 24550726, Free PMC Article
  4. Genome-wide assessment of AU-rich elements by the AREScore algorithm. Spasic M, et al. PLoS Genet, 2012 Jan. PMID 22242014, Free PMC Article
  5. Transcriptional regulation by CHIP/LDB complexes. Bronstein R, et al. PLoS Genet, 2010 Aug 12. PMID 20730086, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cation binding IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7115-PA
CG7115-PB
CG7115-PC
CG7115-PD
CG7115-PE
NP_001260214.1
NP_001260215.1
NP_001260216.1
NP_609154.1
NP_723320.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7821151..7825350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273286.1 → NP_001260215.1  uncharacterized protein Dmel_CG7115, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260215.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCH3
    Conserved Domains (1) summary
    cd00143
    Location:58 → 429
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

  2. NM_001273285.1 → NP_001260214.1  uncharacterized protein Dmel_CG7115, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260214.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D8FT19
    Conserved Domains (1) summary
    cd00143
    Location:56 → 427
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

  3. NM_164774.3 → NP_723320.1  uncharacterized protein Dmel_CG7115, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723320.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XZ28
    Related
    FBpp0079146
    Conserved Domains (1) summary
    cd00143
    Location:111 → 482
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

  4. NM_001273287.1 → NP_001260216.1  uncharacterized protein Dmel_CG7115, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260216.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XZ28
    Conserved Domains (1) summary
    cd00143
    Location:111 → 482
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

  5. NM_135310.4 → NP_609154.1  uncharacterized protein Dmel_CG7115, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609154.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XZ28
    Related
    FBpp0079147
    Conserved Domains (1) summary
    cd00143
    Location:111 → 482
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D8FT19 D8FT19
M9PCH3 M9PCH3
Q9XZ28 Q9XZ28

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