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CG14535 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34073, updated on 9-Dec-2024

Summary

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Official Symbol
CG14535provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031955
Locus tag
Dmel_CG14535
See related
AllianceGenome:FB:FBgn0031955
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG14535; DmKIF26; KIF26; KIF26A/B
Summary
Predicted to enable microtubule binding activity. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Orthologous to human KIF26A (kinesin family member 26A) and KIF26B (kinesin family member 26B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG14535 in Genome Data Viewer
Location:
28D2-28D2; 2-29 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7844905..7855475, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7844905..7855475, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene lectin-28C Neighboring gene TweedleE Neighboring gene Proctolin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evidence for involvement of the alcohol consumption WDPCP gene in lipid metabolism, and liver cirrhosis. O'Farrell F, et al. Sci Rep, 2023 Nov 23. PMID 37996473, Free PMC Article
  2. Analysis of the kinesin superfamily: insights into structure and function. Miki H, et al. Trends Cell Biol, 2005 Sep. PMID 16084724
  3. The kinesin motor Klp98A mediates apical to basal Wg transport. Witte L, et al. Development, 2020 Aug 14. PMID 32665246, Free PMC Article
  4. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article
  5. Reconstructing the phylogeny of 21 completely sequenced arthropod species based on their motor proteins. Odronitz F, et al. BMC Genomics, 2009 Apr 21. PMID 19383156, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
NOT enables ATP hydrolysis activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
enables microtubule binding ISS
Inferred from Sequence or Structural Similarity
more info
  
NOT enables microtubule motor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
NOT involved_in microtubule-based movement ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG14535-PA
CG14535-PB
Kinesin11
kinesin superfamily protein 26

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7844905..7855475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298797.1 → NP_001285726.1  uncharacterized protein Dmel_CG14535, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285726.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VLW2
    UniProtKB/TrEMBL
    X2J924
    Conserved Domains (1) summary
    cl22853
    Location:44 → 394
    Motor_domain; Myosin and Kinesin motor domain

  2. NM_135312.2 → NP_609156.1  uncharacterized protein Dmel_CG14535, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609156.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VLW2
    UniProtKB/TrEMBL
    X2J924
    Related
    FBpp0079186
    Conserved Domains (1) summary
    cl22853
    Location:44 → 394
    Motor_domain; Myosin and Kinesin motor domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VLW2.2 Q9VLW2
X2J924 X2J924

Gene LinkOut

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