U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG8460 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34115, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
CG8460provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031996
Locus tag
Dmel_CG8460
See related
AllianceGenome:FB:FBgn0031996
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8460
Summary
Predicted to enable oligosaccharide binding activity. Predicted to be involved in carbohydrate metabolic process. Located in endomembrane system. Is expressed in adult head. Orthologous to human CHID1 (chitinase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG8460 in Genome Data Viewer
Location:
28F1-28F1; 2-30 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8197193..8198813)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8197193..8198813)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44116 Neighboring gene Post-GPI attachment to proteins 5 Neighboring gene antisense RNA:CR44119 Neighboring gene Sodium/solute co-transporter-like 5A11

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family. Funkhouser JD, et al. BMC Evol Biol, 2007 Jun 26. PMID 17594485, Free PMC Article
  2. Tramtrack is genetically upstream of genes controlling tracheal tube size in Drosophila. Rotstein B, et al. PLoS One, 2011. PMID 22216153, Free PMC Article
  3. The biology of insect chitinases and their roles at chitinous cuticles. Rabadiya D, et al. Insect Biochem Mol Biol, 2024 Feb. PMID 38184175
  4. Manual curation and phylogenetic analysis of chitinase family genes in the Asian citrus psyllid, Diaphorina citri. Shippy TD, et al. GigaByte, 2022. PMID 36824529, Free PMC Article
  5. Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators. Li J, et al. Cell, 2020 Jan 23. PMID 31955847, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables chitin binding IEA
Inferred from Electronic Annotation
more info
  
enables oligosaccharide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG8460-PA

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8197193..8198813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135346.4 → NP_609190.2  uncharacterized protein Dmel_CG8460 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609190.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95RR3, Q9VLS0
    Related
    FBpp0079207
    Conserved Domains (2) summary
    cd02876
    Location:81 → 402
    GH18_SI-CLP; Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome. SI-CLP has a glycosyl ...
    smart00636
    Location:86 → 393
    Glyco_18; Glyco_18 domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VLS0 Q9VLS0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous