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mtsh mitoshell [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34141, updated on 9-Dec-2024

Summary

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Official Symbol
mtshprovided by FlyBase
Official Full Name
mitoshellprovided by FlyBase
Primary source
FLYBASE:FBgn0262598
Locus tag
Dmel_CG7795
See related
AllianceGenome:FB:FBgn0262598
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7795; Dmel\CG7795
Summary
Involved in spermatogenesis. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See mtsh in Genome Data Viewer
Location:
29A4-29A4; 2-31 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8316889..8319908, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8316889..8319908, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Oligosaccharide transferase gamma subunit Neighboring gene Methyltransferase like 14 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene stratum Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel predicted bromodomain-related protein affects coordination between meiosis and spermiogenesis in Drosophila and is required for male meiotic cytokinesis. Bergner LM, et al. DNA Cell Biol, 2010 Sep. PMID 20491580, Free PMC Article
  2. The SUMO Ligase Su(var)2-10 Controls Hetero- and Euchromatic Gene Expression via Establishing H3K9 Trimethylation and Negative Feedback Regulation. Ninova M, et al. Mol Cell, 2020 Feb 6. PMID 31901448, Free PMC Article
  3. Mitochondrial Differentiation during Spermatogenesis: Lessons from Drosophila melanogaster. Vedelek V, et al. Int J Mol Sci, 2024 Apr 3. PMID 38612789, Free PMC Article
  4. Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila. Janic A, et al. Science, 2010 Dec 24. PMID 21205669
  5. Cytokinesis in Drosophila male meiosis. Giansanti MG, et al. Spermatogenesis, 2012 Jul 1. PMID 23094234, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. molecular cloning of the mitoshell gene (CG7795); it encodes a novel protein with a bromodomain-related region; speculate that Mitoshell may participate in transcriptional regulation of spermatogenesis-specific genes
    Title: A novel predicted bromodomain-related protein affects coordination between meiosis and spermiogenesis in Drosophila and is required for male meiotic cytokinesis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
mitoshell
Names
CG7795-PC
CG7795-PD
mtsh-PC
mtsh-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8316889..8319908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135364.3 → NP_609208.2  mitoshell, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609208.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VLP4

  2. NM_164806.3 → NP_723373.2  mitoshell, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723373.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IPF9, Q8MSA8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MSA8 Q8MSA8
Q9VLP4.2 Q9VLP4

Gene LinkOut

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